Hades II throws you into a chaotic underworld, and choosing the right weapon is key to survival! There's no single 'best' weapon – it truly depends on your playstyle. However, some shine brighter than others. The Sister Blades are fantastic for fast, aggressive builds, allowing you to dart in and out of combat. The Witch's Staff, while slower, packs a serious punch and benefits from ranged Boons. For those who prefer a more defensive approach, the Moonstone Axe offers excellent crowd control and high damage potential with the right upgrades.
Ultimately, experimentation is crucial. Consider your preferred Boons and Daedalus Hammer upgrades. Do you love lightning-fast attacks? Area-of-effect damage? A powerful, singular strike? Try them all and find the weapon that resonates with your inner god! Don't be afraid to invest Darkness in each weapon to unlock its full potential. Good luck, and may your runs be blessed!